Evaluation of Effects of Losartan on Random Pattern Skin Flap Model of Rats
نویسندگان
چکیده
منابع مشابه
Evaluation of the effects of losartan on a random pattern skin flap model in rats.
BACKGROUND Losartan, a drug with antiinflammatory properties, has been shown to prevent ischemic injury in various organs. The purpose of the present study was to investigate the effects of losartan on ischemic skin flaps and on flap survival. METHODS A 3x9 cm dorsal flap was elevated in 24 Sprague-Dawley rats. Rats received the following treatment for seven days: Group I (n=8): 10 mg/kg losa...
متن کاملFavorable effects of progesterone on skin random flap survival in rats
Objective(s): The aim of this study is to determine the effects of progesterone treatment on the survival of random skin flaps. Materials and Methods: McFarlane flaps were established and 40 male rats were randomly assigned to the progesterone-treated as the test group or normal saline-treated as the control group. Progesterone or normal saline (10 mg/kg) was administered intraperitoneally onc...
متن کاملOral administration of alanyl-glutamine and glutamine improve random pattern dorsal skin flap survival in rats
Objective(s): Skin flap necrosis is the most common postoperative side effect in reconstructive surgeries. Glutamine (GLN) has been shown to accelerate wound healing process. The purpose of this study was to evaluate the effects of GLN either in free form or in the dipeptide form along with L- alanyl (Ala-GLN) on random skin flaps survival in rats.Materials and Methods: Dorsal skin flaps with c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Turkish Journal of Trauma and Emergency Surgery
سال: 2011
ISSN: 1306-696X,1307-7945
DOI: 10.5505/tjtes.2011.98958